The New Indian Journal of OBGYN. Epub Ahead of Print

Association of BMI and AMH in infertile women with and without polycystic ovarian disease

Seema Saran, Himanshu Roy, Swapnil Singh

ABSTRACT

Objective: Infertility and obesity are problems that have been on the rise in the past two decades. Anti-mullerian hormone (AMH) is a useful marker of ovarian reserve and is frequently estimated while treating infertility patients. Our study aims at evaluating the relationship between serum AMH levels and BMI in infertile patients with and without polycystic ovarian disease. Methods: This cross-sectional study was conducted on 200 women attending the OPD for infertility treatment from February 2019 to January 2020 at a semi urban hospital in India. All patients underwent gynaecological examination and basic infertility investigations including BMI calculation. Serum AMH levels were estimated for all patients. Women were divided into 2 groups - those with PCOD and without PCOD. Results: Mean overall AMH level was 4.86± 4.44 ng/ml. There was no significant correlation between BMI and AMH levels in the non PCOD group (r - 0.022, p > 0.05). However, in the PCOD group, there was inverse correlation between BMI and AMH levels which was significant (r - 0.285, p< 0.05). Conclusion: There is no significant correlation of BMI and AMH levels in infertile women without PCOD. However, in women with PCOD, there is significant inverse correlation of BMI with serum AMH levels.